Search on: PREGNANCY-ASSOCIATED ALPHA 2-MACROGLOBULINS 
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Descriptor English:   Pregnancy-Associated alpha 2-Macroglobulins 
Descriptor Spanish:   alfa 2-Macroglobulinas Asociadas al Embarazo 
Descriptor Portuguese:   alfa 2-Macroglobulinas Associadas à Gravidez 
Synonyms English:   Pregnancy-Associated alpha 2-Globulins
Pregnancy-Associated alpha 2-Glycoproteins  
Tree Number:   D12.776.124.790.720.100.500
D12.776.780.675
Definition English:   Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of pregnant women but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5). 
History Note English:   2004 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38251 
Unique Identifier:   D045384 

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